2023
Epigenetic and transcriptional plasticity drive inflammation in Cystic Fibrosis
Dinan AM*, Eneje O*, Brown KP, Burden F, Morse M, Prinjha R, Frontini M, Floto RA.
bioRxiv. 2023 (preprint).
(*Equal contributors)
Zika viruses encode multiple upstream open reading frames in the 5′ viral region with a role in neurotropism
Lefèvre C, Cook GM, Dinan AM, Torii S, Stewart H, Gibbons G, Nicholson AS, Echavarría-Consuegra L, Meredith LW, Lulla V, Kenyon JC, Goodfellow I, Deane JE, Graham SC, Lakatos A, Lambrechts L, Brierley I, Irigoyen N.
bioRxiv. 2023 Apr 20.
Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria
Remes C, Khawaja A, Pearce SF, Dinan AM, Gopalakrishna S, Cipullo M, Kyriakidis V, Zhang J, Dopico XC, Yukhnovets O, Atanassov I, Firth AE, Cooperman B, Rorbach J.
Nucleic Acids Research. 2023 Jan 11.
2022
Ribosome profiling of porcine reproductive and respiratory syndrome virus reveals novel features of viral gene expression
Cook GM, Brown K, Shang P, Li Y, Soday L, Dinan AM, Tumescheit C, Mockett AA, Fang Y, Firth AE, Brierley I.
Elife. 2022 Feb 28;11:e75668.
A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit
Rebelo-Guiomar P, Pellegrino S, Dent KC, Sas-Chen A, Miller-Fleming L, Garone C, Van Haute L, Rogan JF, Dinan A, Firth AE, Andrews B.
Nature Communications. 2022 Feb 17;13(1):1-4.
2020
A case for a negative-strand coding sequence in a group of positive-sense RNA viruses
Dinan AM, Lukhovitskaya NI, Olendraite I, Firth AE.
Virus Evolution. 2020 Jan;6(1):veaa007.
Hybrid gene origination creates human-virus chimeric proteins during infection
Ho JS, Angel M, Ma Y, Sloan E, Wang G, Martinez-Romero C, Alenquer M, Roudko V, Chung L, Zheng S, Chang M, Fstkchyan Y, Clohisey S, Dinan AM, …, Marazzi I.
Cell. 2020 Jun 25;181(7):1502-17.
2019
C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis
Gopalakrishna S, Pearce SF, Dinan AM, Schober FA, Cipullo M, Spåhr H, Khawaja A, Maffezzini C, Freyer C, Wredenberg A, Atanassov I, Firth AE, Rorbach J.
Nucleic Acids Research. 2019 Sep 26;47(17):9386-99.
Comparative analysis of gene expression in virulent and attenuated strains of infectious bronchitis virus at subcodon resolution
Dinan AM, Keep S, Bickerton E, Britton P, Firth AE, Brierley I.
Journal of Virology. 2019 Sep 1;93(18):e00714-19.
An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells
Lulla V, Dinan AM, Hosmillo M, Chaudhry Y, Sherry L, Irigoyen N, Nayak KM, Stonehouse NJ, Zilbauer M, Goodfellow I, Firth AE.
Nature Microbiology. 2019 Feb;4(2):280-92.
2018
Ribosome profiling of the retrovirus murine leukemia virus
Irigoyen N, Dinan AM, Brierley I, Firth AE.
Retrovirology. 2018 Dec;15(1):1-8.
Transcriptional and translational landscape of equine torovirus
Stewart H, Brown K, Dinan AM, Irigoyen N, Snijder EJ, Firth AE.
Journal of Virology. 2018 Sep 1;92(17):e00589-18.
2017
ASXL gain-of-function truncation mutants: defective and dysregulated forms of a natural ribosomal frameshifting product?
Dinan AM, Atkins JF, Firth AE.
Biology Direct. 2017 Oct 16;12(24):1-6.
2016
Functional characterization of the Mycobacterium abscessus genome coupled with condition specific transcriptomics reveals conserved molecular strategies for host adaptation and persistence
Miranda-CasoLuengo AA, Staunton PM, Dinan AM, Lohan AJ, Loftus BJ.
BMC Genomics. 2016 Dec;17(1):1-2.
2014
Relaxed selection drives a noisy noncoding transcriptome in members of the Mycobacterium tuberculosis complex
Dinan AM, Tong P, Lohan AJ, Conlon KM, Miranda-CasoLuengo AA, Malone KM, Gordon SV, Loftus BJ.
mBio. 2014 Aug 5;5(4):e01169-14.